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入学希望の方一般・社会人の方研究者の方同窓生の方在学生の方教職員の方 日本語 (Japanese) Graduate School of Life Sciences, Tohoku University Access sitemap Link Tohoku University HOMEAbout UsAbout UsMessage from the DeanOrganizationMovieResearchLaboratories Department of Integrative Life Sciences Department of Ecological Developmental Adaptability Life Sciences Department of Molecular and Chemical Life SciencesResearchAwardEducationDegree ProgramsCourseSyllabusScheduleStudent LifeAdmissionAdmission InformationApplicationExamination Schedule and Application GuidelinesInformation Session(2024)Admission and Tuition FeesAdmission PolicyVoices from Graduates and Current StudentsAdmissions Q&AInquiries about Entrance ExaminationsFinancial SupportFor StudentsGraduate School&＃039;s Message Board for Students Information about Completion and Advancement to the Doctoral Course ProceduresCertificatesAbout Issuance of Various CertificatesNotice Regarding the Suspension of Operation of the Automatic Certificate Issuing MachinesLeave of absence/withdrawal from universityCampus Life, Various consultation servicesContactAccessLinkSitemapInformationAdmissionResearchAwardSeminarJobNewsAnnouncementOther MENU HOMEAbout UsAbout UsMessage from the DeanOrganizationMovieResearchLaboratoriesResearchAwardEducationDegree ProgramsCourseSyllabusScheduleStudent LifeAdmissionAdmission InformationApplicationExamination Schedule and Application GuidelinesInformation Session(2024)Admission and Tuition FeesAdmission PolicyVoices from Graduates and Current StudentsAdmissions Q&AInquiries about Entrance ExaminationsFinancial SupportFor StudentsGraduate School&＃039;s Message Board for Students Information about Completion and Advancement to the Doctoral Course ProceduresCertificatesLeave of absence/withdrawal from universityCampus Life, Various consultation servicesContactAccessLinkSitemapInformationAdmissionResearchAwardSeminarJobNewsAnnouncementOther 日本語 (Japanese) CLOSE Graduate School of Life Sciences, Tohoku University. Fields Integrative Life Sciences :Cellular Network Research Developmental Dynamics HOME Research Laboratories Developmental Dynamics JAPANESE Developmental Dynamics Genetic regulation of cellular behaviors during animal development During animal development, cells divide, change their shapes, and migrate to form a complex body structure. To study these dynamic cellular behaviors, we use the nematode, Caenorhabditis elegans as a model system. Using gene manipulation and live imaging techniques, we aim to understand how cellular dynamics are regulated genetically and molecularly. We currently focus on multiple microtubule functions, and analyze their temporal and spatial regulation during cell division and morphogenesis of sensory neurons. Another topic of interest is how the shape and size of cells that comprise specific organs (e.g., gonads and intestine) are regulated coordinately during development. Finally, to understand how changes of the genome sequence lead to evolution of cellular dynamics, we aim to establish a new research field called “evolutionary cell biology”, using C. elegans and other closely related nematodes. Research Overview We are studying dynamic cell behaviors during embryogenesis, using the nematode C. elegans as a model system. By extensively using live microscopy and gene manipulation, we currently focus on the following three topics. 1) Spindle formation in mitosis and meiosis: When a cell divides, microtubules organize spindles that play central roles in chromosome segregation. While mitotic spindle microtubules are formed from centrosomes, female meiotic spindles are assembled independently from centrosomes. We are analyzing how these two distinct types of spindles are formed. 2) Assembly of germ granules: Germ granules are RNA and protein complexes (RNP complexes) specifically present in germline cells, that are implicated in germline-specific regulation of gene expression. We are analyzing how germ granules are assembled and segregated specifically into germ cells. 3) Cell shape change during morphogenesis: During morphogenesis, cells change their shape dynamically. We are investigating how this process is temporally and spatially regulated, with a focus on actin and microtubule cytoskeletons. URLs https://devdyn.wixsite.com/sugimoto-lab Faculty Members Professor SUGIMOTO Asako More Spatiotemporal control of microtubule behaviors during mitosis and meiosis Assembly and segregation of germ granules Cell shape change during morphogenesis New techniques for analyzing cellular dynamics Associate Professor NIWA Shinsuke (C) More Assistant Professor HARUTA Nami More Assistant Professor (Cross Appointment) OHTA Midori More ResearchLaboratories Department of Integrative Life Sciences Department of Ecological Developmental Adaptability Life Sciences Department of Molecular and Chemical Life SciencesResearchAward GO TOP Graduate School of Life SciencesTohoku University 2-1-1 Katahira, Aoba-Ku, Sendai 980-8577 Academic Affairs Section Tel : +81-22-217-5706 / Fax: +81-22-217-5704   General Affairs Section Tel : +81-22-217-5702 / Fax: +81-22-217-5704   Contact ・Privacy Policy HOMEAbout UsAbout UsMessage from the DeanOrganizationMovieResearchLaboratories Department of Integrative Life Sciences Department of Ecological Developmental Adaptability Life Sciences Department of Molecular and Chemical Life SciencesResearchAwardEducationDegree ProgramsCourseSyllabusScheduleStudent LifeAdmissionAdmission InformationApplicationExamination Schedule and Application GuidelinesInformation Session(2024)Admission and Tuition FeesAdmission PolicyVoices from Graduates and Current StudentsAdmissions Q&AInquiries about Entrance ExaminationsFinancial SupportFor StudentsGraduate School&＃039;s Message Board for Students Information about Completion and Advancement to the Doctoral Course ProceduresCertificatesAbout Issuance of Various CertificatesNotice Regarding the Suspension of Operation of the Automatic Certificate Issuing MachinesLeave of absence/withdrawal from universityCampus Life, Various consultation servicesContactAccessLinkSitemapInformationAdmissionResearchAwardSeminarJobNewsAnnouncementOther © 2004-2023 Graduate School of Life Sciences, Tohoku University no cache