ジェシカ・ローズ・クラーク

入学希望の方一般・社会人の方研究者の方同窓生の方在学生の方教職員の方 日本語 (Japanese) Graduate School of Life Sciences, Tohoku University Access sitemap Link Tohoku University HOMEAbout UsAbout UsMessage from the DeanOrganizationMovieResearchLaboratories Department of Integrative Life Sciences Department of Ecological Developmental Adaptability Life Sciences Department of Molecular and Chemical Life SciencesResearchAwardEducationDegree ProgramsCourseSyllabusScheduleStudent LifeAdmissionAdmission InformationApplicationExamination Schedule and Application GuidelinesInformation Session(2024)Admission and Tuition FeesAdmission PolicyVoices from Graduates and Current StudentsAdmissions Q&AInquiries about Entrance ExaminationsFinancial SupportFor StudentsGraduate School&＃039;s Message Board for Students Information about Completion and Advancement to the Doctoral Course ProceduresCertificatesAbout Issuance of Various CertificatesNotice Regarding the Suspension of Operation of the Automatic Certificate Issuing MachinesLeave of absence/withdrawal from universityCampus Life, Various consultation servicesContactAccessLinkSitemapInformationAdmissionResearchAwardSeminarJobNewsAnnouncementOther MENU HOMEAbout UsAbout UsMessage from the DeanOrganizationMovieResearchLaboratoriesResearchAwardEducationDegree ProgramsCourseSyllabusScheduleStudent LifeAdmissionAdmission InformationApplicationExamination Schedule and Application GuidelinesInformation Session(2024)Admission and Tuition FeesAdmission PolicyVoices from Graduates and Current StudentsAdmissions Q&AInquiries about Entrance ExaminationsFinancial SupportFor StudentsGraduate School&＃039;s Message Board for Students Information about Completion and Advancement to the Doctoral Course ProceduresCertificatesLeave of absence/withdrawal from universityCampus Life, Various consultation servicesContactAccessLinkSitemapInformationAdmissionResearchAwardSeminarJobNewsAnnouncementOther 日本語 (Japanese) CLOSE Graduate School of Life Sciences, Tohoku University. Field Integrative Life Sciences :Brain and Nervous System Research HOME Research Researcher JAPANESE Assistant Professor AOKI Sho Campus Katahira campus Laboratory Brain Development Tel +81-22-2117-6229 E-mail sho.aoki.d3＠tohoku.ac.jp Google Scholar https://scholar.google.com/citations?user=FTBrE64AAAAJ&hl=ja&oi=ao   I am determined to uncover the neural mechanisms underlying learning of novel actions and behavioral flexibility. I believe our discoveries help not only build the knowledge of human being, but eventually contribute to the better health and education. Career 2008 Faculty of Sports and Health Sciences, Juntendo University, B.Sc. 2010　Graduate School of Arts and Sciences, University of Tokyo, M.Sc. 2010-2013　Japan Society for the Promotion of Science, Doctoral Fellowship（DC1） 2010-2013　Graduate School of Arts and Sciences, University of Tokyo, Ph.D. 2012-2013　Erasmus Medical Center Rotterdam, Dept of Neuroscience, Visiting Scholar 2013-2017　Okinawa Institute of Science and Technology, Neurobiology Research Unit, Researcher 2017-2019　 Japan Society for the Promotion of Science, Postdoctoral Fellowship（PD） 2018-2022　Salk Institute for Biological Studies, Molecular Neurobiology Laboratory, Research Associate 2022 Graduate School of Life Sciences, Tohoku University, Assistant Professor Selected Publications Sho Aoki *,#, Jared B. Smith #, Hao Li #, Xunyi Yan, Masakazu Igarashi, Patrice Coulon, Jeffery R. Wickens, Tom J.H. Ruigrok *, Xin Jin *. An open cortico-basal ganglia loop allows limbic control over motor output via the nigrothalamic pathway. eLife, e49995 (2019).   Sho Aoki, Patrice Coulon, Tom J.H. Ruigrok *. Multizonal cerebellar influence over sensorimotor areas of the rat cerebral cortex. Cerebral Cortex. 29(2): 598-614 (2019).   Sho Aoki *, Andrew W. Liu, Yumiko Akamine, Aya Zucca, Stefano Zucca, Jeffery R. Wickens *. Cholinergic interneurons in the rat striatum modulate substitution of habits. European Journal of Neuroscience. 47(10): 1194-1205 (2018).   Sho Aoki *, Andrew W. Liu, Aya Zucca, Stefano Zucca, Jeffery R. Wickens *. Role of striatal cholinergic interneurons in set-shifting in the rat. Journal of Neuroscience. 35(25): 9424-9431 (2015).   Sho Aoki, Yamato Sato, Dai Yanagihara *. Lesion in the lateral cerebellum specifically produces overshooting of the toe trajectory in leading forelimb during obstacle avoidance in the rat. Journal of Neurophysiology. 110(7): 1511-1524 (2013). Activities in Academic Societies Society for Neuroscience Recent Activities ○ We identified striatal cholinergic interneurons that enable behavioral flexibility（Aoki et al., J Neurosci., 2015） ○ We uncovered a neural circuit mechanism for connecting emotion to action（Aoki et al., eLife, 2019） ○ We found a neural network mechanism for procedural motor learning（Aoki et al., 投稿準備中） ○ We are investigating neural mechanisms that support or interfere motor learning ○ We are also studying the balance between exploration and exploitation that underlies behavioral flexibility and their neural substrates Message to Students Let’s chat something about science. It must be a fun time! 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